For projects located in moderate climates that are striving to meet aggressive energy reduction goals, natural ventilation is a must. But implementing natural ventilation will introduce potentially humid air to interior spaces, which can be problematic. At Scripps Institute of Oceanography’s new MESOM laboratory project, offices and workspaces utilize operable windows to meet their primary ventilation requirements, leaving only the internally located laboratories requiring mechanical ventilation. To facilitate cross ventilation, we organized the building into a narrow bar and provided ample operable windows and large doors which open onto exterior work areas. The scientists at MESOM often work between their exterior work yard and their interior labs to prepare scientific instruments which go out to sea. Large open doors facilitate their workflow and allow breezes into the building.